Dermarite PeriGuard® Antimicrobial Protectant Barrier Cream 3-1/2 oz Tube PeriGuard® is a specially formulated antimicrobial barrier ointment with Zinc Oxide. PeriGuard® also contains the antimicrobial agent Chloroxylenol which makes it a perfect candidate for residents prone to urinary tract infections. PeriGuard® is also enriched with vitamins A, D and E. PeriGuard® leaves skin soft and supple. It leaves no heavy hard to remove residue, which allows skin to breath and heal quickly. Use to treat diaper rash, dry skin or in a prevention program.